Though we cannot call it a miracle cure yet, but if the conclusions Phase 1 trial held recently for EXO-C24 (a new drug) are supported in other trials, then we may celebrate the first true therapy for COVID-19.
If the EXO-C24 can truly assist most Coronavirus patients get back to their feet within five days, then the drug won’t just save more lives, it would address mutations and complement vaccines.
During the Phase 1 trial at the Ichilov Medical Center of Tel Aviv, the EXO-C24 revealed that within three to five days, 29 out of every 30 recipients can be cured. All the 30 COVID-19 patients recovered after developing moderate to severe COVID-19.
The issue with the recovery from COVID-19 is that the patient’s immune system may develop a serious reaction in at-risk groups. This will lead to multiple organ failure and at the end, death. This phenomenon is referred to as a cytokine storm.
EXO-C24 isn’t seen as an anti-viral that looks to terminate the virus. However, this can be handled by the immune system, and this is why many people just recover from the virus without any treatment. This drug helps to deal with the cytokine storm, and prevents the overreaction from happening.
This drug makes use of exosomes. These are tiny carriers that can move materials between cells to deliver the CD24 protein to the lungs. Professor Nadir Arber spent many decades researching this protein.
In an interview with The Times, Arber said:
The preparation is inhaled once a day for a few minutes, for five days. The preparation is directed straight to the heart of the storm — the lungs — so unlike other formulas… which selectively restrain a certain cytokine, or operate widely but cause many serious side effects, EXO-CD24 is administered locally, works broadly and without side effects.Professor Nadir Arber
Shiran Shapira, who is a researcher, told the paper that:
This protein is located on the surface of cells and has a well known and important role in regulating the immune system.Shiran Shapira