Blind Mice with Glaucoma have regained their sight via this technique that boosts youthful gene expression, all thanks to Harvard Medical School’s researchers. The researchers were able to help some mice who were suffering from glaucoma regain their sight.
The retinal ganglion cells and the optic nerves in these mice were restored to a new state. This was achieved by expressing certain transcription factors, proteins that turn on and off genes.
The study sheds light on the mechanisms of aging, and identifies new potential therapeutic targets for age-related neuronal diseases such as glaucoma.Researchers at Harvard Medical School
Dr. David Sinclair conducted a study on ageing in mice. Sinclair also examined how supplement-ready compounds affect aging.
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The science behind the new paper of Sinclair talks about the curious process of methylation. Governed by epigenetics, this means a transformation in the genetic expression of the cell over time. The researchers discovered that methylation in mammalian tissues stops the cells from replicating proteins while encoding a kind of genetic history at the same time.
These data indicate that mammalian tissues retain a record of youthful epigenetic information, encoded in part by DNA methylation, which can be accessed to improve tissue function and promote regeneration in vivo.
In Sinclair’s book, the modern theory of aging was explained. The theory of aging explains that the changes in epigenetic and cells & tissues damage stops the body from reading protein-encoding genes, which results in older genes being transcribed.
These blind mice with glaucoma have now regained their sight with the help of this simple technique. This shows there is advancement in science and the researchers have helped to prove that.